Which clinical sign would necessitate the administration of naloxone (Narcan)?

Which clinical sign would necessitate the administration of naloxone (Narcan)?

• A. Hypertension
• B. Slow respirations
• C. Tachycardia
• D. Extreme agitation

Answer: (B)

Naloxone is used to reverse opioid-induced respiratory depression. Opioids depress the brain’s respiratory centers, causing slowed and shallow breathing, which can lead to hypoxia and danger. Naloxone works by blocking the same opioid receptors, displacing the opioids, and rapidly restoring normal respiration. Therefore, slowed or depressed respirations are the sign that would prompt giving naloxone. The other signs listed—high blood pressure, fast heart rate, or extreme agitation—do not specifically indicate opioid-induced respiratory depression and aren’t the triggers for naloxone unless respiratory depression from opioids is also present. In real situations, you'd support breathing and monitor closely after administration, since naloxone’s effects can wear off and additional doses may be needed.

Naloxone is used to reverse opioid-induced respiratory depression. Opioids depress the brain’s respiratory centers, causing slowed and shallow breathing, which can lead to hypoxia and danger. Naloxone works by blocking the same opioid receptors, displacing the opioids, and rapidly restoring normal respiration. Therefore, slowed or depressed respirations are the sign that would prompt giving naloxone. The other signs listed—high blood pressure, fast heart rate, or extreme agitation—do not specifically indicate opioid-induced respiratory depression and aren’t the triggers for naloxone unless respiratory depression from opioids is also present. In real situations, you'd support breathing and monitor closely after administration, since naloxone’s effects can wear off and additional doses may be needed.